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J Diabetes, 11:971-981
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These immune-mediated events were compounded by intolerable gastrointestinal side effects, including nausea in 59% and vomiting in 37% of participants, along with reports of acute pancreatitis, culminating in a dropout rate of 2634% in Phase 3 trials [65]
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Semaglutide may affect sebaceous gland function and cutaneous immune responses due to its strong metabolic effects, which include reduced lipogenesis, appetite suppression, and modulation of adipose-derived inflammatory pathways [9,10]
