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The top candidates positively affecting steady-state levels of pAkt were abundance of Akt, abundance of PI3K, and abundance of GAB1, while PI3K inactivation, pAkt deactivation, and Gab1 pMet dissociation were the top parameters negatively affecting the steady-state levels of pAkt (Fig

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Cao p, Ionizing irradiation inhibits keloid fibroblast cell proliferation and induces premature cellular senescence

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The diagnostic criteria for IC/BPS, based on the proposed guidelines of the European Society for the Study of Interstitial Cystitis, constituted chronic pelvic pain, pressure, or discomfort perceived to be related to the urinary bladder accompanied by at least one other urinary symptom, such as persistent urge to void or urinary frequency, for more than 6 months, and the exclusion of potentially similar diseases 11,25