glutathione peroxidase production Frontiers Mechanism of glutathione peroxidase (GPx)
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Gain-of-function mutations disrupt this equilibrium by enhancing cation leakage and facilitating the dehydration of RBCs, resulting in hereditary xerocytosis
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C., Batchvarova, M

[ref] As an iron sensor, HFE controls iron intake and regulates the downstream production of hepcidin.[ref] When too much iron is absorbed, whether because of a mutation in the HFE gene or other genes regulating iron, the body stores it in different organs

How does glutathione work (mechanism of action)
