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Hydration needs should be individualized based on activity level, climate, and comorbidities

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Genetic variants inform baseline receptor sensitivity and metabolic potential, but they do not predict whether GLP-1 will trigger or worsen autoimmune activity

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While lifestyle changes like maintaining a balanced, nutrient-dense diet and exercising regularly are essential to achieving and sustaining weight loss, GLP-1 medications can be used as an adjunct to support these efforts

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10.1371/journal.pone.0127811

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