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The incubation of human atrial cardiomyocytes with canagliflozin reduced inflammation and apoptosis, suppressing myocardial NADPH oxidase activity, and improved nitric oxide synthase (NOS) coupling via SGLT1/AMPK/Rac1 signaling [112]

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doi: 10.1371/journal.pone.0193138
PMID 36216945 Lincoff AM et al
